Error 21919303 also fires when MPN (Manufacturer Part Number) is a required item-specific for the category and is missing from the listing. The listing is blocked until MPN is populated.
Many categories require MPN to disambiguate products that share a brand. Feeds frequently include only SKU or GTIN and omit MPN entirely. For products that genuinely have no MPN (handmade, custom), you must explicitly submit 'Does Not Apply'.